Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---GADTRLV--PGCLVKLYRPPKYIGCFDRSILVGAKCIPVQTTWKIKGHDISVWNGCS-TVKGINLPKGWFVKGE------- 2JMB Chain:A ((1-79)) MQHPYVGIWVTADGRIRQELLPN---GRYDEAR--GNRKSAYQGRYEVRGAHINYWDDTGFTADGDFVSANELHHGGMTFYREK

General information: TITO was launched using: RESULT: Template: 2JMB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 220 11352 51.60 172.00 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 51.60 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.246

(partial model without unconserved sides chains): PDB file : Tito_2JMB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2jmb-query.scw PDB file : Tito_Scwrl_2JMB.pdb: