Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVVPPNRSQTGWPRGVTQFGNKYIQ---QTKPLTLERTINLYPLTNYTFGT-----------------KEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQL--GTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN------- 2A6T Chain:A ((1-245)) -----MSFTNATFSQVLDDLSARFILNLPAEEQSSVERLCFQIEQAHWFYEDFIRAQNDQLPSLGLRVFSAKLFAHCPLLWKWHEEAFDDFLRYKTRIPVRGAIMLDM-SMQQCVLVKGWKASSGWGFPKGKIDKDESDVDCAIREVYEETG--------------------FDCSSRINPNEFIDMTIRGQNVRLYIIPGISLDTRFEISKIEWHNLMDLPTFKMKNKFYMVIPFLAPLKKWIKKRNIANNTTKE

General information: TITO was launched using: RESULT: Template: 2A6T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 793 6864 8.66 34.15 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 8.66 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.307

(partial model without unconserved sides chains): PDB file : Tito_2A6T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2a6t-query.scw PDB file : Tito_Scwrl_2A6T.pdb: