Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADSARYTFNMAGIIMHPGEKRVLLRAVQGGWMLPQVEWQADEYSSWKEVARFNREMQGLLDVCLSTVRCLGEDFERATMHFSRIYVMELHSSYDNLPADACWIDIEDLKEFMITPEEHLVWLEEWLAKRDEEERTPWYHPDWL-AKAKVWIEQ-ALAEPEAQPLVSIEQVGVAERGCLLRVQTKENAFYFKALPAFFRHELTLLQHLARYRVGCVPALVAVDEREHRLLMHDFGSKHLDQSLDLADWQE-ALRRYAILQIDHIQIDHIQIDHSAQVEQLEELGCPRLPLATLPDQLERLLTS-EQSLLFDTPTALSLEQVRRLHDALPLIRSLCQELAGYGLPE-TLEHGDLHAQNIALSG-----GDYLYFDWTDSCIAHPFFSLYPFLLDIEARWPEARIRL-REAYLQPWERYAARAQLVEAFELAQRLAPLHLAMLYATLIIPHMKARWEMQHGVPLNLKVLLDRLHDAG------------------------- 3CSV Chain:A ((4-333)) ---------------------------------------------------------------------------------------------------------------------SREDEIRDFLATHGYADWNRTPRYQRLRSPTGAKAVLMDWSPEEGGDT---------------------------------QPFVDLAQYLRNLDIS-APEIYAEEHARGLLLIEDLGDALFTEVINNDPAQEMPLYRAAVDLLIHLH---------------------DAQTPELARLDPETLSEMTRLAFSEYRYAILGDA--AEDNRKRFEHRFAQILSAQLEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNM--RILGIFARLSQRF--GKRHYIEFVPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1313 -19539 -14.88 -68.32 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -14.88 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.237

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: