Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLTDVLDDWPLWGISKQPISANQISILEGGLTNRCYQLSLES---------GEYIIRISAANTAEL-GIDRNVEKTIHQLVSSLNFTSAIRYCDDENRYLIRDYIEGEVLSDNVEDMSHNTLSYMVEQLKALHQVPVEIDLPVVNISEKAEAYWQMLATQQP-----NN----EI-LKMKPLMQVAMSE--PPAGDFCLCHLDPVLANWLYTA-------EGLQLLDWEYAGLAHPLWDLAALFQGIKH------------------SFQQLEKKSKKNSHSEIEQNLENKI--L-----TLYGVSDLVAWRRACMQMEYLSSLWYQAQAKKDSY 5FUT Chain:A ((30-351)) --------------------DEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYG------GAEAMVLESVMFAILAERSLGPKLYGIFPQ--GRLEQFIPSRRLDTEELSLPDISA-EIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFIS-----SYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKI---

General information: TITO was launched using: RESULT: Template: 5FUT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 836 -1579 -1.89 -6.44 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -1.89 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.376

(partial model without unconserved sides chains): PDB file : Tito_5FUT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5fut-query.scw PDB file : Tito_Scwrl_5FUT.pdb: