Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PCVITIDGPYNPKYNFYPSHGRGVTGPHGQVVIGDFTCTVGA--TCNQLTCNAP--QPEYSILGVDS 1AIW Chain:? ((1-62)) ----MGDCANANVYPNWVS-KDWAGGQPTHNEAGQSIVYKGNLYTANWYTASVPGSDSSWTQVGSCN

General information: TITO was launched using: RESULT: Template: 1AIW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 228 -1565 -6.86 -26.97 target 2D structure prediction score : 0.84 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -6.86 2D Compatibility (Sec. Struct. Predict.) : 0.84 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.101

(partial model without unconserved sides chains): PDB file : Tito_1AIW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1aiw-query.scw PDB file : Tito_Scwrl_1AIW.pdb: