Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSDYVDDESSVRINRKMELIKVPDESAGNAMIGISYLTREDGKIIADRIKELCNESRYNNSFWEEALYIKDKMMVSAKTVSSKDVIEINTYEQLREIDENSDQLDTDAISVICEAFKINKNDIYNITVLKKGMTNRSFLFECK--GKKYIMRIPGEGTDMLINRREEAEVYNVVNKEKICDNVIYINPDNGYKITEFIENSRVCD--PFNEDDVKRCMDKLRTFHNLKLKVNHE--------------FNILGQMKFYESLWNE-K-S-----------VYDDYELTKANVLSLKKYVEDNVSEKVLTHIDAVPDNFLFAG--DEIRLIDWEYAGMHDPHVDIAXXAGMQDPHVDIAMFAIYS---------LYDREQTDRLIDAYFTGNCD---KKTRLKIYCYIAMCGLLWSNWCEYKRQLG--VEFGEYSLRQYRYAKDFYRIFINESEQIKEELK 2QG7 Chain:E ((109-448)) --------------------------------------------------------------------------------------------------------------------------DSLEFQIING-ITNILIKVKDMSKQAKYLIRLYGPKTDEIINREREKKISCILYNKNIAKKIYVFFT-NG-RIEEFMDGYALSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFDAKANILKLIDFDVLRDSIVEVESLCKRENSPIVLCHCDLLSSNIINTVGGDSISFIDFEYSCPME-------------RAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIREIQPFYICSHINWGLWSLLQGMHSSDFDFINYGMTRLTA--------------------

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 990 -5226 -5.28 -20.49 3D Compatibility (PKB) : -5.28 2D Compatibility (Sec. Struct. Predict.) : 1D Compatibility (Hydrophobicity) : QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: