Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LDSLIEHRSPIFCLVQMCEMLDGGKK---DCT---------RWYKVYPGGSHTF----------QEGGRDTITVTFDNKCKK-SL-----------------SGSTKKRSIGFPTQVVYRS- 1BD2 Chain:D ((1-118)) -QQVKQNSPSLS--VQ--E----GRISILNCDYTNSMFDYFLWYKKYPAEGPTFLISISSIKDKNADGR--FTVFLNKSAKHLSLHIVPSQPGDSAVYFCAAMEGAQKLVFGQGTRLTINPN

General information: TITO was launched using: RESULT: Template: 1BD2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 165 17924 108.63 256.05 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain D : 0.64 3D Compatibility (PKB) : 108.63 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.404

(partial model without unconserved sides chains): PDB file : Tito_1BD2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1bd2-query.scw PDB file : Tito_Scwrl_1BD2.pdb: