Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANE----VERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL 4O6V Chain:C ((9-239)) --MTIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGK-GEALAKELGGIGVTGSNQSNDDLQKLVDQTLEKWGRIDVLVNSAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPAMQKQKSGVIINISTAWAF-EPSAMFPTSAVFRAGLASFTKIFADTYAAENIRMNNVLPGWIDSLPTTEERR-------------ESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLT-

General information: TITO was launched using: RESULT: Template: 4O6V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1288 -77764 -60.38 -342.57 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain C : 0.74 3D Compatibility (PKB) : -60.38 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_4O6V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4o6v-query.scw PDB file : Tito_Scwrl_4O6V.pdb: