Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LKPRFTLAEAKAMARDEFHVRVAAIVELN-SYDDQNYK--VTAENGAVYVLKVHNGVESRDEGLLDAQSQLYERLRRKGVA-APYPVDSNP--LADGDATFALRLLEWVDGDLLSSKEITPGLLATTGAFLGRIRLALDDFDHAALH----RVHLWDGRQFPALASFADGLVD----AG-------CDVDKAADVHRAIANFDAVVAPA-AAQLPLATLHGDFNDANVLVGA-ETLGVLDIGDSVHSWRVNDVAVGMAYVVV 3I1A Chain:B ((3-250)) -KQPIQAQQLIELLKVHYGIDIHTAQFIQGGADTNAFAYQADS-ESKSYFIKLKYGY--H--D--EINLSIIRLLHDSGIKEIIFPIHTLEAKLFQQLKHFKIIAYPFIHAPNGFTQNLTGKQWKQLGKVLRQIHETSVPISIQQQLRKEIYSPKWREI----VRSFYNQIEFDNSDDKLTAAFKSFFNQNSAAIHRLVDTSEKLSKKIQPDLDKYVLCHSDIHAGNVLVGNEESIYIIDWDEPMLAPKERDLMFIGGGV--

General information: TITO was launched using: RESULT: Template: 3I1A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 731 -1071 -1.47 -4.76 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -1.47 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.346

(partial model without unconserved sides chains): PDB file : Tito_3I1A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3i1a-query.scw PDB file : Tito_Scwrl_3I1A.pdb: