Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSNNNNPLTRDEILSRYFPQYRPAVATSQGLSGGSCIIAHDTHRVVLRRHHDPDAPPAHFLRHYRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDAD--------ELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAG----LRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFE-YRWRQTGEQQFIRLADETWRQLRMKG--- 4WW7 Chain:A ((4-257)) ---------EFIDKVSSYLT---PDVDIAPISQGAAIVFTTTTHPYLPRAKDSHQKYIIKYRPRTLNESRLLAKLYLIPGLCVPQLIACDPYNGFIWLEFLGEDLPGGHGFSNLKNFLWMHDQDPY-------SDLVATTLRKVGRQIGLLHWNDYC-----------------HGDLTSSNIVLVRDGARWTPHLIDF---GLGSV----------SNLVEDKGVDLYVLERAILSTHS-KHAEKYNAW---IMEGFEEVYREQGAKGAKKLKEVTKRFEEVRLRGRKR

General information: TITO was launched using: RESULT: Template: 4WW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 985 -33901 -34.42 -153.40 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -34.42 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.185

(partial model without unconserved sides chains): PDB file : Tito_4WW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ww7-query.scw PDB file : Tito_Scwrl_4WW7.pdb: