Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MTGIVDDEALDASLRAWIEATTGSGITAIQRVSGGAFRTSCRVDLDGAPGAAFLKIDLGSAPRTPFDLRREHELLTRLDGRARAPRTIGWHEGATAMAMHCLPGEARWAGIADEAHR----------DRIERSFAEALVECHAVDIASLALDHLP----PGLTIGEAIRREL-DMWEELLDA------NVADPDPLTLFAFRWLRHRLPADDRPAVLVQGDA--GPGNFLFDA--ERVTGLVDWEMTHLGHPLE-DLGCVLARSLVQ--PMASAERLLSLY-----RAASGRDWTMDELLYATIL---------VMARFSVPIALALESRHTGMDFGLT--------NGYFRLSQISLIRLIARAEG----------LTLDET---------PPASGPRPAIGFE--FDYLRDVLGTIVRPAIDDPYVQYRLDGAI--GLIGYLRAALADDTAGPRGDRDELRALYADRIAE-------GDIATTLQEFLAE-ALWRETLMKDMLGPLHGGRVKL---------------------------------- 5SVD Chain:A ((5-589)) QMFFGVLDREELEYFKQAESTLQLDAFEAPEEKF---QFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSN---MDFGTAIINTSNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALP--EERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFP

General information: TITO was launched using: RESULT: Template: 5SVD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1872 34468 18.41 80.91 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 18.41 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.342

(partial model without unconserved sides chains): PDB file : Tito_5SVD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5svd-query.scw PDB file : Tito_Scwrl_5SVD.pdb: