Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNKMKNHKITKLGGLNNSNYLLECENNKYVLRIPSKDNK--NNFSEENFVLIFANL-NKLSPPIIYHNK-------------DNGILISKFLEDSKVNMSTFTSLEFLEKLSINLRKLHILKCEH-I---FNPFE-HIRKNFHILKS---KNF------NFHQDIDLVL-NKLNILEEKLSKNMTIGLCHNDLNSSNVLYYN----KNVLFIDFEFSAMCDIFFDLATVSW-M-L---DEKKRYFLIKSYFGYYSY--ELMEKLENYLFVVKLWNASWSFLKSLNT---NSTYDYKLGGNMIIDDLLSTL 6EF6 Chain:A ((45-347)) -------SLRLL-NLSENATYLVEDGEHQSILRVHRQDYHQPHEIESELDWLAALRTDSDVTVPTVVPARDGRRVVTVDPADVPRHVVHFEMVGGAEPDEES-LTLDDFQTLGRITASLHEHSQRWTRPAGFGRFSWDWEHCLGDTPRWGRWQDAEGVGASETALLTRAQDLLHRKLEEYGSGPDRYGLIHADLRLANLLVDSSTPQRTITVIDFDDCGFGWYFYDFGTAVSFIEHDPRLGEWQESWVAGYRSRRELPAADEAMLPSFVFLRRLLLLAWMGSHTHSRESATKAISYAAGSCALAERYLS--

General information: TITO was launched using: RESULT: Template: 6EF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1113 -2315 -2.08 -9.08 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -2.08 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.316

(partial model without unconserved sides chains): PDB file : Tito_6EF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ef6-query.scw PDB file : Tito_Scwrl_6EF6.pdb: