Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------PIPRIIGPCEVKVLKA-GVSQHLAYFKMGRETTKTFFVPVPGGSTYLFELRTTYDCTATILRWTMPRDYG 1D1L Chain:A ((1-61)) MEQRITLKDYAMRFG--QTKTAKDLGVYQS-AINKAIHAGRKIFLTINADGSVYAEEVK------------PWPSN--

General information: TITO was launched using: RESULT: Template: 1D1L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 163 7336 45.01 141.08 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 45.01 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.106

(partial model without unconserved sides chains): PDB file : Tito_1D1L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1d1l-query.scw PDB file : Tito_Scwrl_1D1L.pdb: