Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGCPVDIMINNQRYHWT-NKPRNSSFEIVVQGQTVATVHLDEDCNVRL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 4HG6 Chain:B ((36-702)) PWIIPLRPLAETAQVGPLFRLQGQQARAAFRLFLPTEAVGGTLTLAQRSSIDILPESSQIIVRMNDQEIGRFTPRQFGALGAVTMPLGEAVRAGDNLVTIEAQHRHRIYCGADAEFDLWTEVDLSQSGVALPAAAIGTEPTSFIAALTAQAESGRPVEIRTPTPPDEATLRTLAQALGRPLPDEALPLALSKPWSAETGPTYARITLLPSDADRVSIRRGGDGAVVLVLEHPPEGSPNASLVADLLGATPTLPPPTLPQIPPGRVVTLADMGVDTILTDNRYFNRDIDFQLPDDWLLLASQKAQIGID---YGFAGGLPEGALLLVKVNGTTVRMLPLDRDAAPVKPRLDIRFPARLLHPGPNRLSFESVIPGNPPDQPCPASAGDLMQVLSSTDLEVPPSPRMQMADMARDLAQVTPASVHPATPDGLARTLPFMAAFREVPDAAPVDLTVAGLHDIATVPLNEEGLTPRLLALTLLPSTGPPANALAPLGAAPGEGVMPPLVESNWSDRAQTFVQATLQPVIQTVRRMLRPGDGNLAEWLATRKGTAMLLAPEPGKLWVILGPEAEPARVAEALAMAPRSPGGPRGQVAVLGSDGRWSSWSKPGLLPELREPVSLDNVRSVVGNVASARPPLLLGGMLGLAWISAAIAVGFVLRTR

General information: TITO was launched using: RESULT: Template: 4HG6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 67 -11 -0.16 -0.25 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain B : 0.49 3D Compatibility (PKB) : -0.16 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.49 QMean score : 0.407

(partial model without unconserved sides chains): PDB file : Tito_4HG6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4hg6-query.scw PDB file : Tito_Scwrl_4HG6.pdb: