Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNKMKNHKITKLGGLNNSNYLLECENNKYVLRIPSKDNKN--NFSEENFVLIFANLNKLSPPIIYHNKDNGILISKFLEDSKVNMSTF--TSLEFLEKLSINLRKLHILKC--EHIFNPFEHIRKNFHILKSKNFNFHQDIDLVLNKLNILEEKLSKN-MTIGLCHNDLNSSNVLYYNKNVLFIDFEFSAMCDIFFDLA--TVSWMLDEKKRYFLIKSYFGYYSYELMEKLENYLFVVK-----LWNASWSFLKSLNTNSTYDYKLGGNMIIDDLLSTL 3DXQ Chain:A ((22-271)) --------PLERLGGLTN----LVFRAGDLCLRIPGK----YINRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLS--NVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEGKFNANQDEELMRAYFG---GEARPAERGRVVIYKAMCDLLWTL-WGLIQLANDNPVDDFR--------------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1069 -19082 -17.85 -82.96 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -17.85 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: