Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----NDSDCHIWIK--DNSDIVFGYSKAVTGQTAVVEI---SQGPHKKEQFKFATAADQTNKKDCTAGLAGERSFPAGWRIKTF------ 1Y8R Chain:C ((14-97)) GDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKK-LKESYCQRQGVP-MNSLRFLFEGQRIADNHTPKELGME----EEDVIEVYQEQTGG

General information: TITO was launched using: RESULT: Template: 1Y8R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 248 18441 74.36 267.26 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain C : 0.68 3D Compatibility (PKB) : 74.36 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.396

(partial model without unconserved sides chains): PDB file : Tito_1Y8R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1y8r-query.scw PDB file : Tito_Scwrl_1Y8R.pdb: