Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWQAISRLLSEQVGEGEIELRNELPGGEVHAAWHLRYA-GHDFFVKCDEREM--LRGFTAEADQLELLSRSKTVVVPKVWAVGSD-----RDYSFLVMDYLSPRPLDA---HNAFILGQQLARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAAEKGITFGNIDAIVEHVQQRLAS---HQPQPSLLHGDLWSANCALGPDGPYIFDP-ACYWGDRECDLAMLPLH-----TDQPPQIYDGYQSVSPLPLDFLDRQPIYQLYTLLNRARLFGGQHLATAQKAMDRLLAV 1ZYL Chain:A ((14-265)) --DTIMDALFE-HGIRVDSGLTPL-NSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVND-EVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFI--HRP----TIGLNEYLIEPRKLFED------ATLIPS--GLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRD-GPMFVDLDDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGL----------------------------------

General information: TITO was launched using: RESULT: Template: 1ZYL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 937 -36002 -38.42 -155.18 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -38.42 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.243

(partial model without unconserved sides chains): PDB file : Tito_1ZYL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1zyl-query.scw PDB file : Tito_Scwrl_1ZYL.pdb: