Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTELNASEFRSLITSVFPELTASVFKLAAKSWDSLAVDVDDTLIFKFPRHPAAERALVKEAGVLDIVRPSL--SMAVPDMHIHDG--PPIFSSHAKLDGEHLIAEDYDALGQGVRRHLADDLARFYAELHVLDADRLRQAGVGA-IQPWQSPDAVRTKALPLLPPDIGRFAEAVIADFEAL--PPDPHGTVFGFFDGHGWNMAFDHAQGRLNGIYDFADSGFGPLHQEFIYSN-F----ISADLTARIVSAYEMLTGRKL-DRRRIAILTGFHRLSELAELADDPAHVDLMVQNVATWAAVAAHVG 5IQC Chain:A ((9-302)) --ATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHN--DFSCNHLLLDG-NNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRT-------

General information: TITO was launched using: RESULT: Template: 5IQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1257 -18864 -15.01 -67.13 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -15.01 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_5IQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5iqc-query.scw PDB file : Tito_Scwrl_5IQC.pdb: