Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVRIPDELNAQRRLGPDWENWLDRLPRLCDEIVSDWGLTVVG-EPT-NGFASIVIPVSTSDGDAMLKVGFDSSPETEHEHLALTYWAGDGA--VTMFRAD--------PARHAMLLEQLHSRDLSQEWDLQACEIVAGFYSRLHRPAPP-----RLRPLTGFVDRWLGALEADAREM-------------PV-------PRRLIDHALNRGRAFV--------DDPASVGRIIHGDLHYENVLAADREPWLVIDPQPM-SGDPHYELAPMLWNRWDEMDGYLRESIQRRFYTLVEAAGLDDDRARDWVIVRMILNAHWAVEDAKRMNRALDADERDWITRCIAVAKAVQR 2Q83 Chain:A ((18-292)) -----------------------KLTELAENVLQGWDVQAEKIDVIQ----ALVWKVHTDSGAVCLKRIHRPEKKALFSIFAQDYLAKKGMNVPGILPNKKGSLYSKHGSFLFVVYDWIEGRPFELTV-KQDLEFIMKGLADFHTASVGYQPPNGVP-IFTKLGRWPNHYTKRCKQMETWKLMAEAEKEDPFSQLYLQEIDGFIEDGLRIKDRLLQSTYVPWTEQLKKSPNLCHQDYGTGNTLLGENEQIWVIDLDTVSFDLPIRDLRKMIIPLLDTTGVWDDETFNVMLNAYESRAPLT--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2Q83.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 770 -10137 -13.16 -45.05 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -13.16 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.209

(partial model without unconserved sides chains): PDB file : Tito_2Q83.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2q83-query.scw PDB file : Tito_Scwrl_2Q83.pdb: