Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLTDVLDDWPLWGISKQPISANQISILEGGLTNRCYQLSLE-SGEYIIRISAANTAELGIDRNVEKTIHQLVSSL-NF-TSAIRYCDDE---N----RYLIRDYIEGEVLSDNV--EDMSHNTLSYMVEQLKALHQVPVEIDLPV----VN---ISEKAEAYWQMLATQQP--NNEILKMKPLMQVAMSEPPAGDFCLCHLDPVLANWLYTA--EGLQLLDWEYAGLAHPLWDLAALFQGIKHSFQQLEKKSKKNSHSEIEQNLENKILTLYGVSDLVAWRRACMQMEYLSSLWYQAQAKKDSY 5IGI Chain:A ((24-285)) ---------------------HGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAE--VSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA-VIQPGSSTPDWVVPQDSEVFAE-SFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDD-D-SSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVF--GEEGLAKLLL-----TYEAAGG-----RVWPRLAHHIAERLAFGAVTYALFALDSG-----

General information: TITO was launched using: RESULT: Template: 5IGI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1011 -8554 -8.46 -35.94 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -8.46 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_5IGI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5igi-query.scw PDB file : Tito_Scwrl_5IGI.pdb: