Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHDIAALLHKAAPRSEIAEVLPRSGGQLATVFE-VRRIAAAPLIIKLYSPEWAWKQAKEIHVYDLLAPHLGTAIPQVVHAEPEGETHAFTVMTMLTGVPLCETTA---PDYQVVYKQLGELLTAIHRIPQPAYGYLTDEVLEPLPSNDAYMRRQFAKKLQEFEELGGDRALHARLTEYVEQHSGLFASSSRPVLCHNDFHEGNVLVDPDT--WQVQGIVDVENAIAADPLIDLAKTQYYSIKN-DQAKLSGLLTGYGELP--SD-W-VERTAVYRLYHALELWDWFRLIGVIDPLESIAADLVSLLGTSRVAGRPDAVR 3CSV Chain:A ((7-278)) --DEIRDFLAT-H-GYADWNRTP--------RYQRLRSPTGAKAVLMDWSPEEGGDTQPFVDLAQYLRN-LDISAPEIYAEEH---ARGLLLIEDLGDALFTEVINNDPAQEMPLYRAAVDLLIHLHDAQTPELARLDPETLSEMTR---LAFSEYRY---AILGD-AAEDNRKRFEHRFAQILSA-QLEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNMRILGIFA--------------------------------

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1113 -15749 -14.15 -62.25 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -14.15 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.260

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: