Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKTEPSINLSLKRLVENPSYADACDILDERPLEFWLPTIEVILSQHQLAKKTVLRISNGSNALFDI-DNEYILKLVPPNWDYQGISEVTSLTLLNLANHSENLSLAVPKMIGFGRVDNWFYVIMTKLKGLSMATVWPDLNTAQKL-PLVKQLGQFMTELHQITSTQAFTPDPRLSVD-WPEYIKGLISDSVPRHARKGVSPELVTQISDYLQAADSDFNDIHA-VFIHMDLHPWNLMVEKHHGHYRLCGVVDFGDALVGNCQLLELATPIIFVCQGNKTLIDEL-VANYSPLNEVYLDRQVLQRQLMAVSLI-RPACDFNFVLQQVPQSGKRDSWQAIAKQLFPLYKGRPA------------------------ 3CSV Chain:A ((4-333)) ------SREDEIRDFLATHGYAD------------------------WNRTPRYQRLRSPTGAKAVLMDW-------SPE------EGGDTQPFVDLAQYLRNLDISAPEIYAEEHARG--LLLIEDLGDALFTEVINN--DPAQEMPLYRAAVDLLIHLHDAQTPELARLDPETLSEMTRLAFSEYRYAIL-----GDAAEDNRKRFEHRFAQILSAQLE-GDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGH-RAYDLVSLLQDARRDVPAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNMRILGIFARLSQRFGKRHYIEFVPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1355 -10122 -7.47 -34.66 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -7.47 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.332

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: