Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSDYVDDESSVRINRKMELIKVPDESAGNAMIGISYLTREDGKIIADRIKELCNESRYNNSFWEEALYIKDKMMVSAKTVSSKDVIEINTYEQLREIDENSDQLDTDAISVICEAFKINKNDIYNITVLKKGMTNRSFLFECKG----KKYIMRIPGEGTDMLINRREEAEVYNVVNKEKICDNVIYINPDNGYKITEFIENSRVCDP--FNEDDVKRCMDKLRTFHNLKLKVNHE---FN----ILGQMKFYESLWNE-K-----SVYDDYELTKANVLSLKKY----------------VEDNVSEKVLTHIDAVPDNFLFAGDEIRLIDWEYAGMHDPHVDIAXXAGMQDPHVDIAMFAIYSL------------------YDREQTDRLIDAYFTGNCD------K----KTRLKIYCYIAMCGLLWSNWCEYKRQL--GVEFGEYSLRQYRYAKDFYRIFINESEQIKEELK 3MES Chain:B ((73-410)) ----------------------------------------------------------------------------------------------------------------------------IEVKQIFSGLTNQLFVVSIVNELKHPRILFRIYGKHV--FYDSKVELDVFRYLSNINIAPNIIADFP--EGRIEEFIDGEPLTTKQLQLTHICVEVAKNMGSLHIINSKRADFPSRFDKEPILFKRIYLWREEAKIQVSKNNQIDKELYSKILEEIDQLEELIMGGEKFSMERALELKLYSPAFSLVFAHNDLQENNLLQTQNNIRMIDYEYSAINF-------------AGADIANYFCEYIYDYCSEKQPYFKFKYEDYPCEELRKLFISVYLSQTLQEQVMPSQQIVHIMTKAVEVFTLISHITWGLWSIA----SVEFDFTEYANTRFTHYLQKKKELI-----------

General information: TITO was launched using: RESULT: Template: 3MES.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 955 -29017 -30.38 -112.90 3D Compatibility (PKB) : -30.38 2D Compatibility (Sec. Struct. Predict.) : 1D Compatibility (Hydrophobicity) : QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_3MES.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3mes-query.scw PDB file : Tito_Scwrl_3MES.pdb: