Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------P---IPRIIGPCEVKVLKAGVSQHLAYFKMGRETTKTFFVPVPGGSTYLFELRTTYDCTATILRWTMPRDYG 1DTJ Chain:A ((4-77)) MKELVEMAVPENLVGAILGK-GGKTLVEYQELTGARIQISKKGE-----FLPGTRNRRVTITGSPAATQAAQYLISQRVT-

General information: TITO was launched using: RESULT: Template: 1DTJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 196 8280 42.24 133.55 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 42.24 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.239

(partial model without unconserved sides chains): PDB file : Tito_1DTJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1dtj-query.scw PDB file : Tito_Scwrl_1DTJ.pdb: