Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKLSTMLKVDRTVDKEGQSPIAEHILEQWEH-------DQGSAQFF-RSSTNFVYIFRKG---------GETCFLRFAESTERTRAEIEAEMALLNFLASQGMTVATPVVSKNGRCVATVETDLGTFHAVVFTQLPGREVEIEE-LSPAQFEIWGATLGKLHAMTHRYQDPKV---AARGTWRDHLTLVR-NA---VPTDEPRVQAECDYLTSFLAA-LPVTEMNSGLIHGDFELDNLRWQD-------ETLAMFDFDECAASWYIADVAFALRDLFETG------------VDLS-HPSFRAFIRGYCEQYSL-------------DEELLSHLPTFMRLVNLIIYAKLVRATDLTQDQDYPEWCTSLLLKLENWKQNYKTSLLSIPV 5FTG Chain:A ((11-372)) --------------------RAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYG------EAMVLESVMFAILAERSLG-PKLYGIFP------------Q--GRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISS--IEFGYMDYAQARFDAYFHQ----------

General information: TITO was launched using: RESULT: Template: 5FTG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1061 -14923 -14.06 -53.68 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -14.06 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_5FTG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5ftg-query.scw PDB file : Tito_Scwrl_5FTG.pdb: