Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDAAPPPPGLRAWARRQVG--PITAVRDVSHPRPGSRVWHLELGGRLDVFLKAASGP---VAYRRESFAYRHAVPAL--GQGSAPQLIESS--AQHLGLLLTAIPGRPLAELDV---PPAVRHEAYRQAGVLLARLHQAGELRGEHRTEAEEALRRTAHGAEKHLAAAGDRVSGAERRLVLRLAGELLV-L-GPVLLGFLHGDAWERNMLWS-GRRT-AWVDFERARFGAVVQDLVAMYCGAW-SEEPGLRPAFFRGFGRELSAQEEHALTCLSALDAVSCLGWAPGQGDLQVAARGRRALDRLMGAYA 5IQC Chain:A ((12-303)) -------VKAMKYLIEHYFDNFKVDSIEIIGSGY-DSVAYLVN----NEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNV-KIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISEC-TID-NKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTY---

General information: TITO was launched using: RESULT: Template: 5IQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1239 6486 5.23 23.58 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 5.23 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.417

(partial model without unconserved sides chains): PDB file : Tito_5IQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5iqc-query.scw PDB file : Tito_Scwrl_5IQC.pdb: