Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTYTFDQVEKAIEQLYPDFTINTIEISGEGNDCIAYEINRDFIFKFPKHSRGSTNLFNEVNILKRIHNKLP--LPIPEVVFTGMPSETYQMSFAGFTKIKGVPLTPLLLNNLPKQSQNQAAKDLARFLSELHSINISGFKSNLVLDFREKINEDNKKIKKLLSRELKGPQMKKVDDFYRDILENEIYFKYYPCLIHNDFSSDHILFDTEKNTICGIIDFGDAAISDPDNDFISLMED-DEEYGMEFVSKILNHYKHKDIPTVLEKYRMKEKYWSFEKIIYGKEYGYMDWYEEGLNEIRSIKIK 6CGG Chain:A ((19-298)) ------------IEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN--KGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDE---LSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDI-SECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESF-MERLNATTVFEGKKCLCHNDFSCNHLLLDG-NNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEI------

General information: TITO was launched using: RESULT: Template: 6CGG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1257 35842 28.51 130.33 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 28.51 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.472

(partial model without unconserved sides chains): PDB file : Tito_6CGG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6cgg-query.scw PDB file : Tito_Scwrl_6CGG.pdb: