Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------GECHITIWEGNTPIGTEIAIEGRE--YVTIAGYQCNAGAGCTAHCIGLPKNLKERGVYH 3GGQ Chain:A ((6-149)) SRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTIQQHSKTFFVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAG--------PVSISAVAVLA

General information: TITO was launched using: RESULT: Template: 3GGQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 128 3722 29.07 75.95 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : 29.07 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.166

(partial model without unconserved sides chains): PDB file : Tito_3GGQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ggq-query.scw PDB file : Tito_Scwrl_3GGQ.pdb: