Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPSHLTHIWRLLKWGRTLARHGALTGIERDPLTPTPVRRLVRVARLGARVPRQPRYADAFQSIGPAAIKLGQTLATRPDLVGEDAANDLLRLQDALPPVPFATIRAQMEQSFGRPLETLYSRFDEAPVGAASIAQVHRAVTT-DGRDVAVKVIRPGVIDQFNRDIQTYEWAAAHVEMLGGEVARLRPRLVIANMKRWTARELDLRREAASASELGEAMEAMPGYRVPAIDWDRTTGKVMTMEWIDGVKISDRDALIAAGHD--VKEIAARLVNAFLRQAIAEGFFHADMHQGNLFVT--ANGDIVAIDFGIMGRIDRRARMWLAEILYGLITGNYRRVAEIHFEAQYVPGHHNVEEFATALRAVGEPMRGKPVRELSVGGMLDGLFAITRDFDMQTQPHLLLLQKTMVMVEGVATALDPDINLWETSGPYVKEWLRAELGPEAKAADAL------IENVRILQRL-PGLVKRIEEAFPEKGGAPPPPPLTEVRLIR--VGSGWRYMLVALLAGLAGAGAMAAATTFL 1KOB Chain:A ((23-374)) ---------------------------------------------------------------------------------INDYDKFYEDIWKKYVPQPVEVK--------QGSVYDYYDI--LEELGSGAFGVVHRCVEKATGRVFVAKFIN----------------------------------------TPYPLDKYTVKNEISIMNQL-----HHPKLINLHDAFEDKYEMVLILEFLSGGELFDRIAAEDYKMSEAEVINYMRQACEGLKHMHEHSIVHLDIKPENIMCETKKASSVKIIDFGLATKLNPDEI-------VKVTTATAEFAAPEIVDREPVGFYTDMWAIGVLGYVLLSGLSPFAGED------DLETLQNVKRCDWEFDEDAF-----------------SSVS--PEAKDFIKNLLQKEPRKRLTVHDALEHPWLKGDHSNLTSRIPSSRYNKIRQKIKEKYADWPAPQPAIGRIANFSSLRKHRPQEYQIYDSYFDRKEA-------

General information: TITO was launched using: RESULT: Template: 1KOB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1783 -13886 -7.79 -41.08 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -7.79 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.177

(partial model without unconserved sides chains): PDB file : Tito_1KOB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1kob-query.scw PDB file : Tito_Scwrl_1KOB.pdb: