Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------SPDRGLSRMCCVYKIHPGGNIWSTKKGEQAWFRRRFSKYEVMAYDRCNLEWGF---SGKPRGLTF 1K3R Chain:A ((93-163)) PHHPTGKPVTGEYRQGLTVKRVKKGTLVDIGADKLALCREKLTVNRIMSFRVVRLGKEILIEPDEPEDRYW

General information: TITO was launched using: RESULT: Template: 1K3R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 260 19973 76.82 322.14 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 76.82 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_1K3R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1k3r-query.scw PDB file : Tito_Scwrl_1K3R.pdb: