Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAPFSIKQADIQQQLTAAIQKHFPAVEIADIRFELV-GGLSSKSWRIRGPGIEWLARRQSPTERKMGVDRQREFALLRRMSAIGLAPRPLLWRD--DWLIVEWVPGR-IATSDEFL-MMLANGEVARVLSQLHRLPRSGH-PLDIKMLFAQHWQLMDPHR--RSPVLLRAHHYFQ---RAPLPTPLALAPLHLDVHAENLLITPQGTMLIDWEYASDGDIAFELAFIVRASQMDSMAQRYFLQSYQRHRRGFSVNRLQQQMRQWFPWVDYLVLMWFEIRWQQTK-NPEFLADIPALYHRLQLGHRLQPD 3DXQ Chain:A ((2-283)) ----------MTDEARAKLAAIPMLA--GYTGPLERLGGLTNLVFRA----GDLCLRIPGK-----YINRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLS--NVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEGKFNANQDEELMRAYFGGEA---RPAERGRVVIYKAMCDLLWTLWGLIQLANDNPVDDFRAYADGRFARCKA-------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1224 -3255 -2.66 -12.33 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -2.66 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.363

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: