Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTTERAEFDADAAEAILRRACAVADLDPDGIEILRLGDHAVFRIDGGRVISRVGRGADRLASVRREVAVARWLADKEYPAARLVT-DAEQPIVIEDHPVTFWEGLADG-DT--------YASTAEMGVLLRRLHELEAPPF-SLPRLQPFDKVASRLERAVIPESTRAFLRSMARDLEAEYGRLEFSLPSGHLHGDFNVGNVLRDAAGHPRVIDLDGFATGPREWDLMQTAMYYDSFGWHTEAEYADFVVGYGFD---VREWAGYAVLRSVRELLMVTWLSQNAGANPRAADEVQKRVATLRSGGSRRDWAPF 3DXQ Chain:A ((25-262)) ---------------------------------RLGGLTNLVFRA--GDLCLRIPGK---YINRANEAVAAREAAKAGVS-PEVLHVD-------PATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLS-NVTLPAGYHDVVREAGGVRSALAA--HPLPLAACHCDPLCENFLDTG-ERMWIVDWEYSGMNDPLWDLGDLSVEGK----FNANQDEELMRAYFGGEARPAERGRVVIYKAMCDLLWTLWGLIQLA----------------------------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 992 -14638 -14.76 -67.15 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -14.76 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.274

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: