Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDAQGSLVHELK-SLPC-WPA---PVQAIRPL-TGLSGGSLLIELCD--------GRRYVARSQNAQLQMQAVSRERERQVLCAIGEQVARSD-FLPQVLFYNARWLVVSWLEGSPWPHTLADDACAQRHLVTLMRRFHPVDSE-LQ-L-DIPSRLQFYRQQLSAEK--Q---PE--------ALFSLCARFASLRSPCWWFPVLAHHDIHPGNVVSDG-------ATLALIDWEYAARSPLACELILLFEANGFN------------------RAQRQQFCRYYAEAIYSTETVYAADSKCVGSSAAALEDWLHRLQQDIASWQPWCEMLMAMWSAIRFEQT-DDVQYAVWRDNYLKAAEQSLGKRE 5FTG Chain:A ((8-373)) ---TRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYG-------EAMVLESVMFAIL----AERSLG-PKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQN------DF-ENLSTEEKSI-I-KEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQK----

General information: TITO was launched using: RESULT: Template: 5FTG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1080 -23588 -21.84 -83.05 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -21.84 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.510

(partial model without unconserved sides chains): PDB file : Tito_5FTG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5ftg-query.scw PDB file : Tito_Scwrl_5FTG.pdb: