Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTTERAEFDADAAEAILRRACAVADLDPDGIEILRLGDHAVFRIDGGRVISRVGRGADRLASVRREVAVARWLADKEYPAARLVT-DAEQPIVIEDHPVTFWEGLADG-DT--------YASTAEMGVLLRRLHELEAPPF-SLPRLQPFDKVASRLER-AVIPESTRAFLRSMARDLEAEYGRLEFSLPSGHLHGDFNVGNVLRDAAGHPRVIDLDGFATGPREWDLMQTAMYYDSFGWHTEAEYADFVVGYGFD---VREWAGYAVLRSVRELLMVTWLSQNAGANPRAADEVQKRVATLRSGGSRRDWAPF 3DXQ Chain:B ((25-262)) ---------------------------------RLGGLTNLVFRA--GDLCLRIP-------NRANEAVAAREAAKAGVS-PEVLHVD-------PATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLSTKNVTLPAGYHDVVREAGGVRSALAA--HPLPLAACHCDPLCENFLDTG-ERMWIVDWEYSGMNDPLWDLGDLSVEGK----FNANQDEELMRAYFGGEARPAERGRVVIYKAMCDLLWTLWGLIQLA----------------------------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 972 -16169 -16.63 -75.20 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -16.63 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.296

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: