Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --RPCR-VDL-YEFVHTKPGLTSWSWVHRFNGDARRA-SLFRAMGYLCSVDYN-CKNFHCEKLTSWRW-- 2VQC Chain:A ((4-73)) TLNSYKMAEIMYKILEKKGELTLEDILAQFEISVPSAYNIQRALKAICERHPDECEVQYKNRKTTFKWIK

General information: TITO was launched using: RESULT: Template: 2VQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 167 2083 12.47 33.59 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 12.47 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.277

(partial model without unconserved sides chains): PDB file : Tito_2VQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2vqc-query.scw PDB file : Tito_Scwrl_2VQC.pdb: