Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------------CVIGLTFNGNWVPNNRFVISPG----GKFSFIANYVII-PVRLDESCHWHQDLAENAKPVIIPSGYGIKSC---------------------------------------------------------- 1KRR Chain:A ((2-201)) NMPMTERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEVEKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIG---RNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREINDRDKHYYFKDYKVES

General information: TITO was launched using: RESULT: Template: 1KRR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 110 -4269 -38.81 -67.76 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : -38.81 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.287

(partial model without unconserved sides chains): PDB file : Tito_1KRR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1krr-query.scw PDB file : Tito_Scwrl_1KRR.pdb: