Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEQDGQKLFLKRNSNP------------FIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNE----MKQTRVAHLLKKIHNSRPLLSMLKRM------EM-EPITPEIMLNKINASLSREV---------------LTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSD--RDELFLVDWEGAMIADPAIDIGMLLYNYV----------PQQQWSEWLETYGVQES----LNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI 2QG7 Chain:E ((133-432)) -----QAKYLIRLYGPKTDEIINREREKKISCILYNKNIAKKIYVFFT--NG---RIEEFMDGYALSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFDAKANILKLIDFDVLRDSIVEVESLCK-RENSPIVLCHCDLLSSNIINTVGG-DSISFIDFEYSCPMERAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIREIQPFYICSHINWGLWSLLQGMH--------------------

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 764 6500 8.51 31.10 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain E : 0.64 3D Compatibility (PKB) : 8.51 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.311

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: