Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHPAAQPTNQTSSHSPASPSNTEPCEQQSLKQQLLKQQPLKEQSLKQQSREQQLHTWLNEVFPN--QSLQHEKIPGDASFRSYHRLTVDNQHYIVMDAPPAKESVKEFIAVGNLMA-GYVHVPKMIATDE-----QQGFIVLEDLGNTDFADVIAK-DLTDAGELAKTARYYQQAMQEILAIQKIDINDAKAVIPSYDD--ALLRREMGLFSDWFLPYIGVKMTPDLETLWQDLQSDIIQQV---IAQPQVVVHRDFHSRNLMVLSH-SDELGVIDFQDAVIGAYTYDLASLLRDAYI--------------NYDENWVNTHLAHYHQLAQLDKSLAEFTVDFNIMSMQRHLKVLGIFVRLFERDGKDRYLVNLPKVFNDLLTCLKAISQWDKRPTFDKFADWMTAAAAPAFQQKIQG 3DXP Chain:A ((20-327)) ------------------------------------------------RFDTEALEAWMRQHVEGFAGPLSVEQFKG-QSNP-TFKLVTPGQTYVMRAKPG---AIEREYRVMDALAGTDVPVAKMYALCEDESVIGRAFYIMEFVSGRVLWDQSLPGMSP-A----ERTAIYDEMNRVIAAMHTVDYQAIG--LGDYGKPGNYFQRQIERWTKQYKL-----SETESIPAMDSLMDWLPQHIPQEDADLTSIVHGDYRLDNLMFHPTEPRVLAVLDWELSTLGHPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGRPI-TGD-WNFYLAFSMFRIAGILQGIMKRVV-------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1146 -13450 -11.74 -50.18 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -11.74 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.295

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: