Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLPRRPDADPAALLAGLDRS-L--AGLGLTEVGEGFDNIAYAVRSPS-GARLLLRVSKVADPVERARVLTKDVALLEFANRH-SSLTTNEVIAADAHAGALLLTEVTGRTADQIR------------PTDRVAFAATMATFLTRLHTAPVVEAALVTE---MDPRSAAQWLVDTATAWAAVADRTPVTLRDRVDEFLVGPAPSDVRRITFCHNDLGDEHVVLSEDGGHVRGVIDWSDAVLGDPARDLGLLTLDFGPGIVDALIDDYHGPTG---ADFRGRVLWFAATAGVEGLAWRLANARPWQVTADRLHDVLAVLA 5UXA Chain:A ((6-285)) -----------KQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDW-VLRLPRREDVM---PRTKVEKQALDLVNKYAISFQAPNWIIYT--EELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFG--VGENLWNRWQAWLNDD-DMWPKKTGLIHGDVHAGHTMIDKDA-NVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSG------------------

General information: TITO was launched using: RESULT: Template: 5UXA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1080 7419 6.87 28.87 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 6.87 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.385

(partial model without unconserved sides chains): PDB file : Tito_5UXA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxa-query.scw PDB file : Tito_Scwrl_5UXA.pdb: