Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMDDKEILQLLRNDFGVSVCNLKRVKSGNIKTVFSFTYERKEYVIRFSKGNNEFETEQFLYK-LTHKNDHMARLIKIGTY-KNLYYSITERVKGCPLKELNLSKVKTIIPQLIESVTCIHQTDLTPSCGYG-WIKDGNGCFSSFRELI----ETHFKQEQNGFWNDWYTLFEDSFLDYDSFMTLYKEMVRLSPYSDGQRFLTHGDFHFSNIFSDGKMITGIIDWGNVMYGDFILDIAMLHMLYPSLNFKEAFKNYYNTHQIKVENYDKRFICMSLFKGLDTLRFAAKTGDRPFYKSLLNYLQELIAQKKAEDSSYFSHSYKK 3W0Q Chain:A ((11-274)) -------VEKFLIEKFG-SVSDLMQLSEGEESRAFSFDVGGRGYVLRVNSCADGFYKDRYVYRHFASAALPIPEVLDIGEFSESLTYCISRRAQGVTLQDLPETELPAVLQPVAEVMDAIAAADLSQTSGFGPFGPQGIGQYTTWRDFICAIADPHVYH--------WQTVMDDTV--SASVAQALDELMLWAEDCPEVRHLVHADFGSNAVLTDNGRITAVIDWSEAMFGDPLYEVANIFFWRPWLACMEQQARYFERRHPELAG-SPRLRAYMLRIGLDQL----------------------------------------

General information: TITO was launched using: RESULT: Template: 3W0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1176 -31927 -27.15 -124.23 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -27.15 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_3W0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3w0q-query.scw PDB file : Tito_Scwrl_3W0Q.pdb: