Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQEKDRAVVTELLQKAGREDFIPLQENQLAGDGSSRRFYRLASGGETLIAV-LPAGEEAKDRAESRAAYHIGGYLLACGTPVPAIYGWDEASGGLLFQDLGNTRLQDVAH-TEEGR-QLYRQLVRALAGMNCRARGIDSSWCWDSPCYDRSLMLER-ESGYFLRAFWQGL--LGQEVPIGLAEEFSSLADAVSLYSTD-FFLHRDFQSRNIMIH-----AGRPSIIDFQGGRRGPLGYDLASLLYDPYVDLDEDFRAL-LWEDYLAALGAQIDISREDFAKQYSLLACQRSL-QIIGAFSWLSAVAKKTFFVQFIRPSLLNLEKILSAPYYQNYR-VLRQTVRRGLSLYR----- 3CSV Chain:A ((4-333)) ---SREDEIRDFLATHG-----------YADWNRTPRYQRLRSPTGAKAVLMDWSPEEGGD---TQPFVDLAQYLRNLDISAPEIYAEEHARGLLLIEDLGDALFTEVINNDPAQEMPLYRAAVDLLIHLHDAQTP-------ELARLDPETLS-EMTRLAFSEYRYAILGDAAEDNRKRFEHRFAQILSAQL--EGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMI-----DHYIQATGVDESHFRSAYAVIAVQR-NMRILGIFARLSQRFGKRHYIEFVPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1421 -36145 -25.44 -119.68 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -25.44 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: