Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ISSPESLSDEEFEKFCCVYIVNLGKP--DQREWPVLTGKEVWFEHKRKKYDVMAFDSCNLVWGRRGEPKGVTF 6BQ6 Chain:A ((134-188)) --------DEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEG----------

General information: TITO was launched using: RESULT: Template: 6BQ6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 57 5599 98.23 105.64 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 98.23 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.178

(partial model without unconserved sides chains): PDB file : Tito_6BQ6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6bq6-query.scw PDB file : Tito_Scwrl_6BQ6.pdb: