Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPSHLTHIWRLLKWGRTLARHGALTGIERDPLTPTPVRRLVRVARLGARVPRQPRYADAFQSIGPAAIKLGQTLATRP----DLVGEDAANDLLRLQDALPPVPFATIRAQMEQSFGRPLETLYSRFDEAPVGAASIAQVHRAVTTDGRDVAVKVIRPGVIDQFNRDIQTYEWAAAHVEMLGGEVARLRPRLVIANMKRWTARELDLRREAASASELGEAMEAMPGYRVPAIDWDRTTGKVMTMEWIDGVKISDRDALIAAGHDVKEIAARLVNAFLRQAIAEGFFHADMHQGNLFVTANGDIVAIDFGIMGRIDRRARMWLAEILYGLITGNYRRVAEIHFEAQYVPGHH--NVEEFATALRAVGEPMRG-------KPVRELSVGGMLDGLFAITRDFDMQTQPHLLLLQKTMVMVEGVATALDPDINLWETSGPYVKEWLRAELGPEAKAADALIENVRILQRLPGLVKRIEEAFPEKGGAPPPPPLTEVRLIRVGSGWRYMLVALLAGLAGAGAMAAATTFL 5YK0 Chain:A ((50-445)) -----------------------------------------DEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQL---SPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVA--SAPKVVIQEWIEGVPMAEIIRHG-TTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFA-----------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5YK0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1580 -5540 -3.51 -14.46 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -3.51 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.246

(partial model without unconserved sides chains): PDB file : Tito_5YK0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5yk0-query.scw PDB file : Tito_Scwrl_5YK0.pdb: