Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSALDEVEKV-LWDHYGLRGPFEVTALAAEGRNNSLVAFRSPGGAFV-WKQGSSALAPVQQREFAL-LAWLAEQDLP----FRMAAPLRTLAGAWGW-EGGRGLNVLLPLLPG-ERLPETADAWHALG-TALNAL-HAALARFPLEGAPRLLDWAKLGDLHPRVPDPLALSFEQPDLWGDEA-TLH-SWRLAFGEMLWRVRDAYAALPHQVVHGDFNSVNV-LFGGGG-VSAVLDFEFACPGPRL-LDVATAL----------------SEVLVRPEPEWALAQAFLRGYGQLTLQERAALPAALL-LRQAAVGVWG-LGLALEDGPNATTQARLRELGT-VS-AWLKTQGDRLSTG 3DXP Chain:A ((20-359)) RFDTEALEAWMRQHVEGFAGPLSVEQFK--GQSNPTFKLVTPGQTYVMRAKPGA-----IEREYRVMDA-LAGTDVPVAKMYALCEDESVIGRAFYIMEFVSGRVLWDQSLPGMS---PAERTAIYDEMNRVIAAMHTVDYQ-----AIGLGDYGKPGNYFQRQIERWTKQYKLSETESIPAMDSLMDW-------LPQHIPQEDADLTSIVHGDYRLDNLMFHPTEPRVLAVLDWELSTLG-HPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGR-PITGDWNFYLAFSMFRIAGILQGIMKRVVDGTASSAQALDAGKRARPMAEMGWEYAKKAKQ---

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1336 4847 3.63 16.54 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 3.63 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.233

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: