Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence SPDRGLSRMCCVYKI-HPGGNIWSTK-KGEQAWFRRRFSKYEVMAY-DRC---NLEWGFSGKPRGLTF------ 1HZ6 Chain:A ((-2-64)) ----AMEEVTIKANLIFANGSTQTAEFKGT---FEKATS--EAYAYADTLKKDNGEWTVDVADKGYTLNIKFAG

General information: TITO was launched using: RESULT: Template: 1HZ6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 133 1276 9.59 24.07 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 9.59 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.177

(partial model without unconserved sides chains): PDB file : Tito_1HZ6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1hz6-query.scw PDB file : Tito_Scwrl_1HZ6.pdb: