Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------KLCKWTVLNSEGEIIDSGSCLNTEYMKHGD-IHVEFENDCTPIIFGADRVAEKVTIKG------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1ABR Chain:B ((1-267)) IVEKSKICSSRYEPTVRIGGRDGMCVDVYDNGYHNGNRIIMWKCKDRLEENQL--WTL-KSDKTIRSNGKCLTTYGYAPGSYVMIY---DCT----SAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLCMQAQGSNVWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRWVFKNDGSIYSLYDDMVMDVKGSDPSLKQIILWPYTGKPNQIWLTLF

General information: TITO was launched using: RESULT: Template: 1ABR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 57 -1429 -25.06 -30.39 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.53 3D Compatibility (PKB) : -25.06 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.360

(partial model without unconserved sides chains): PDB file : Tito_1ABR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1abr-query.scw PDB file : Tito_Scwrl_1ABR.pdb: