Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----MRRTGAPAQADSRGRGRARGGCPGGEATLS------QPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRI----GGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN----------------------------------------------------- 5WWM Chain:A ((10-323)) DWTASILDQAQAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMD-SYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLIS-HNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFERIITKKITRKQAKFFFNKWLQFEESKTIEYVKAKATEYVAS

General information: TITO was launched using: RESULT: Template: 5WWM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 815 70531 86.54 345.74 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 86.54 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.248

(partial model without unconserved sides chains): PDB file : Tito_5WWM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5wwm-query.scw PDB file : Tito_Scwrl_5WWM.pdb: