Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAACPELVDATFAILASGWHSTAVEVGGRWVFKFPRGAEAEAALLREAAVLRLVRPAV--SLPVPAPQVFAG--PPLFSRHEKLPGGYLLGEDYRRLDEPARQAVGDALGRFYAELHRLPPARMRAVGAL-PVRPWESPAAMRRRALPLLPAAWRERAERLVREYAKLP--ADPLGSIFGFFDGHGWNMAFDSEAGRLNGVYDFADAGIGPLHQEFIYSA-----FIDADLTERIVAAYERFSG-RRLERRRIALL-TAAHRLSELAELADEPRHLPDMLAGALDGLALAEAQGLA 5IQC Chain:A ((22-301)) --YFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHN--DFSCNHLLLDGN-NRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGI-KNIKQEFIENGRKEIYKR----------

General information: TITO was launched using: RESULT: Template: 5IQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1184 -6208 -5.24 -23.34 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -5.24 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.409

(partial model without unconserved sides chains): PDB file : Tito_5IQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5iqc-query.scw PDB file : Tito_Scwrl_5IQC.pdb: