Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIVSDGAVRQRLEAFCRNEFDASELTISRLERIPEGHSGFTYFVDFVDGPHARLVLRLPPPGARPQGPADVARQGRIMTALHHRGLPVPEVHVISEDPGALDGRPFILMEAIDGVRADKA-AAEADNAELARAAVAVMREIHAVDPADTGIGAEPARSLADELDRWSALIAKAPDELTKR------AADLRALLSRSLPADHGPARLVHGDFTYGNLLFRGGTVAAVLDWEIAQLGNPLLDLGSLCVIAKRHDYPNDPNPSGAIRATVEWLIDAYGAAGPVEWTVALSYYKYAAIVGYNTMLHRRGKRPDPIYDLMGDTVIGLIDGAIEILT 1J7L Chain:A ((2-264)) ---AKMRISPELKKLIEK---------YRCVKDTEGMSPAKVYKLVGENENLYLKMT---DSRYKGTTYDVEREKDMMLWLEGK-LPVPKVLHFERH----DGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDTPFKDPRELYDFLKTEKPEE--ELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEE---------QYVELFFDLLGIKPD---WEKIKYYILLD----------------ELF-------------------

General information: TITO was launched using: RESULT: Template: 1J7L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1192 -25457 -21.36 -99.44 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -21.36 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.376

(partial model without unconserved sides chains): PDB file : Tito_1J7L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1j7l-query.scw PDB file : Tito_Scwrl_1J7L.pdb: