Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence GFVNFFKKKASSSTPPPAECEYTVYRNQETDARRRKHS--------QEGTYSFSHQGKAAKNSKQ-NILG-VKVRFD---RECQPHYSSKNQ---- 1C01 Chain:A ((1-76)) -------------------SAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNP-FGWKSIFIQC

General information: TITO was launched using: RESULT: Template: 1C01.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 196 2187 11.16 37.07 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 11.16 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.202

(partial model without unconserved sides chains): PDB file : Tito_1C01.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1c01-query.scw PDB file : Tito_Scwrl_1C01.pdb: